2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

PDF 2.67 MB

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-119613
    Clociguanil
    		Inhibitor
    Clociguanil (BRL 50216), a DHFR inhibitor (IC50: 55.6 nM), is an antimalarial agent. Clociguanil has sympathomimetic and antiarrhythmic action.
    Clociguanil
  • HY-181821
    MMV1581361
    		Inhibitor
    MMV1581361 is a PfATP4 inhibitor and an orally active, transmission-blocking agent with nanomolar activity against Plasmodium falciparum blood-stage isolates. MMV1581361 disrupts sodium ion (Na+) homeostasis in Plasmodium falciparum. MMV1581361 inhibits male gamete exflagellation, reduces oocyst intensity, and blocks transmission of Plasmodium falciparum. MMV1581361 demonstrates efficacy in the humanized Plasmodium falciparum NOD scid IL2Rγnull mouse model. MMV1581361 can be used for the research of malaria.
    MMV1581361
  • HY-118926
    Bioresmethrin
    		Inhibitor
    Bioresmethrin is an insecticide that protects grain. Bioresmethrin against malathion-resistant and susceptible strains R. dominica .
    Bioresmethrin
  • HY-120808
    GSK2188764
    		Inhibitor
    GSK2188764 is a Toxoplasma gondii rhoptry protein 18 (ROP18) inhibitor with reported IC50 values of 7.49 μM against Toxoplasma gondii. GSK2188764 inhibits serine-threonine kinase activity of ROP18 in vitro.GSK2188764 can be used for the research of toxoplasmosis.
    GSK2188764
  • HY-P1992
    Isariin B
    		Inhibitor
    Isariin B is a cyclodepsipeptide isolated from the fungus Isaria felina, which exhibits antimalarial activity.
    Isariin B
  • HY-W751122
    Thiofanox sulfone
    		Inhibitor
    Thiofanox sulfone is an oxidative metabolite of the insecticide/nematicide Thiofanox.
    Thiofanox sulfone
  • HY-19688
    Sitamaquine
    		Inhibitor
    Sitamaquine (WR 6026) is an orally active Antileishmanial agent and Succinate dehydrogenase inhibitor. Sitamaquine accumulates in the acidocalcisomes of Leishmania, induces organelle alkalization, and crosses the plasma membrane of Leishmania via temperature- and energy-independent diffusion. Sitamaquine disrupts oxidative phosphorylation in Leishmania, induces mitochondrial depolarization, oxidative stress, elevated intracellular calcium, plasma membrane depolarization, and Apoptosis-like cell death. Sitamaquine can be used in the research of leishmaniasis.
    Sitamaquine
  • HY-79128S1
    Fmoc-L-Lys (Boc)-OH-13C6,15N2
    		Inhibitor 99.90%
    Fmoc-L-Lys (Boc)-OH-13C6,15N2 is a 15N-labeled and 13C-labled Fmoc-L-Lys (Boc)-OH (HY-79128). Fmoc-L-Lys (Boc)-OH is a lysine derivative.
    Fmoc-L-Lys (Boc)-OH-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-W585869
    Amorphadiene
    		Inhibitor
    Amorphadiene is the precursor to the antimalarial agent artemisinin, which is produced through the amorphadiene synthase (ADS)-catalyzed cyclization of farnesyl pyrophosphate (FPP) yeast.
    Amorphadiene
  • HY-N14189
    Hynapene A
    		Inhibitor
    Hynapene A inhibits Eimeria tenella with a MIC of 123 μM.
    Hynapene A
  • HY-N13885
    Amythiamicin A
    		Inhibitor
    Amythiamicin A is an antimicrobial antibiotic against Gram-positive bacteria (including methicillin-resistant Staphylococcus aureus (MRSA)) and activity against Plasmodium falciparum.
    Amythiamicin A
  • HY-179273
    Proteasome-IN-8
    		Inhibitor
    Proteasome-IN-1 (Compound 130) is a proteasome inhibitor. Proteasome-IN-1 exhibits antiparasitic activity against P. faciparum 3D7.
    Proteasome-IN-8
  • HY-B0803R
    Lumefantrine (Standard)
    		Inhibitor
    Lumefantrine (Standard) is the analytical standard of Lumefantrine. This product is intended for research and analytical applications. Lumefantrine is an active antimalarial molecule used in combination with Artemether as a first- and second-line antimalarial drug.
    Lumefantrine (Standard)
  • HY-114734
    Didesmethylpromazine
    Didesmethylpromazine (Compound 18) is a trypanothione reductase inhibitor with an I50of 1412  μM against T. cruzi trypanothione reductase. Didesmethylpromazine can be used in the research of trypanosome and leishmania infections.
    Didesmethylpromazine
  • HY-W653875
    Azithromycin-d5
    		Inhibitor
    Azithromycin-d5 (CP-62993-d5) is the deuterium labeled Azithromycin (CP-62993) (HY-17506). Azithromycin is a macrolide antibiotic useful for thestudy of a number of bacterial infections.
    Azithromycin-d<sub>5</sub>
  • HY-119766R
    Aramite (Standard)
    		Inhibitor
    Aramite (Standard) is the analytical standard of Aramite. This product is intended for research and analytical applications. Aramite is a miticide and pesticide.
    Aramite (Standard)
  • HY-121657R
    Ornidazole diol (Standard)
    		Inhibitor
    Ornidazole diol (Standard) is an analytical standard for Ornidazole diol. This product is used for research and analytical applications. Ornidazole diol (Ro 11-2616) is the diol of Ornidazole (HY-B0508) which is rapidly hydrolyzed in alkaline solution. Ornidazole (Ro 7-0207) is a 5-nitroimidazole derivative that is antiprotozoan and anaerobic.
    Ornidazole diol (Standard)
  • HY-N15321
    Norselic acid B
    		Inhibitor
    Norselic acid B is a natural compound that can be isolated from the sponge Crella sp. collected in Antarctica. T. Norselic acid B is active against the Leishmania parasite.
    Norselic acid B
  • HY-N13034
    Diuvaretin
    		Inhibitor
    Diuvaretin is an antimalarial agent and a C-phenylated dihydrochalcone. Diuvaretin can be isolated from the roots of U. acuminata. Diuvaretin increases the activity of Caspase-3 and triggers Apoptosis. Diuvaretin exhibits antiparasitic activity against Plasmodium falciparum. Diuvaretin can be used in the research of promyelocytic leukemia and malaria.
    Diuvaretin
  • HY-173567
    WJM664
    		Inhibitor
    WJM664 is a potent Plasmodium falciparum PfATP4 inhibitor. WJM664 shows strong activity against malaria parasites. WJM664 blocks gamete development and transmission to mosquitoes by inhibiting PfATP4-mediated Na+-dependent ATPase activity, and acts on multiple stages of the malaria parasite life cycle.
    WJM664
Parasite Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.